Weight Loss · registered primary completion 2027-07-01 · NCT07104500
4 approved products already carry Weight Loss on label, including AZSTARYS, Ursodiol, Megestrol Acetate, Omega-3-acid ethyl esters. Approval would enter an occupied market.
Registered design for NCT07104500: randomized, triple-masked, 4500 participants (estimated). Primary outcome: Percentage change in body weight from baseline for participants receiving VK2735 after 78 weeks of treatment.
Cash of $502M against operating outflow of $117M per quarter gives roughly 4.3 quarters of runway, clearing the registered primary completion 3.4 quarters out by 0.9 quarters.
116,652,937 shares outstanding against 124,486,664 if every outstanding option, warrant and convertible were exercised. In that case 6.3% of a gain in enterprise value would accrue to those holders rather than to current shareholders.
Designations disclosed: Orphan Drug. These accelerate review and, for Orphan, confer exclusivity if approved; none is evidence of efficacy.
1 distinct molecule in 2 active company-sponsored trials; VK2735 accounts for 2 of them at Phase 3.